منابع مشابه
Predicting CpG Islands and DNA Methlation in the Cow Genome Using DNA Microarray Meta-Analysis and Genome Wide Scanning
DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
متن کاملDna Structural Motifs
■ Abstract DNA secondary structure plays an important role in biology, genotyping diagnostics, a variety of molecular biology techniques, in vitro–selected DNA catalysts, nanotechnology, and DNA-based computing. Accurate prediction of DNA secondary structure and hybridization using dynamic programming algorithms requires a database of thermodynamic parameters for several motifs including Watson...
متن کاملVisualization and Signi cance of DNA Structural Motifs in the Campylobacter jejuni Genome
The genome sequence of Campylobacter jejuni NCTC11168 was analyzed in terms of DNA structural properties (intrinsic curvature, base-stacking energy, and DNA exibility) throughout the chromosome. In addition, we calculated the frequency of DNA repeats in C. jejuni and in chromosomes from 25 other species of the class Proteobacteria. Compared with the average, global repeats are underrepresente...
متن کاملAnalysis of the Campylobacter jejuni Genome by SMRT DNA Sequencing Identifies Restriction-Modification Motifs
Campylobacter jejuni is a leading bacterial cause of human gastroenteritis. The goal of this study was to analyze the C. jejuni F38011 strain, recovered from an individual with severe enteritis, at a genomic and proteomic level to gain insight into microbial processes. The C. jejuni F38011 genome is comprised of 1,691,939 bp, with a mol.% (G+C) content of 30.5%. PacBio sequencing coupled with R...
متن کاملThe thermodynamics of DNA structural motifs.
DNA secondary structure plays an important role in biology, genotyping diagnostics, a variety of molecular biology techniques, in vitro-selected DNA catalysts, nanotechnology, and DNA-based computing. Accurate prediction of DNA secondary structure and hybridization using dynamic programming algorithms requires a database of thermodynamic parameters for several motifs including Watson-Crick base...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2005
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro1300